REARRANGEMENT STUDIES WITH C14: III. THE FRIEDEL–CRAFTS ALKYLATION OF ANISOLE WITH 2-PHENYLETHYL-1-C14 CHLORIDE AND 2-PHENYLETHANOL-1-C14
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چکیده
منابع مشابه
Studies on fluorinated pyrimidines. III. The metabolism of 5-fluorouracil-2-C14 and 5-fluoroorotic-2-C14 acid in vivo.
As one of the initial steps towards the determi nation of the metabolism and mechanism of action of fluorinated pyrimidines, 5-fluorouracil and 5fluoroorotic acid were labeled with radiocarbon in the 2-carbon atom. We have previously reported briefly that fluorouracil is incorporated, as such, into the combined nucleic acids of mouse liver, spleen, and Ehrlich ascites cells (9). The present rep...
متن کاملThe incorporation of formate-C14, glycine-2-C14, adenine-4, 6-C14, and phosphate-P32 into nucleic acids.
nine labeled either with C'4 or N'5. Considerable controversy has developed as to which one of these tracer compounds gives an accurate measurement of the “relativeturnover-rate― of the nucleic acids. In order to determine the “absolute turnover rate― of the nucleic acids, it is necessary to know the specific activity of the immediate precursor of the nucleic acids. Since even the ident...
متن کاملMetabolism of pyruvic acid-2-C14 and hydroxypyruvic acid-2-C14 in algae.
The metabolism of pyruvic acid in the light and dark by Scenedesmus has been examined with two aims: to study the relationship of its metabolism to that of the intermediates of C1402 fixation and to compare its metabolic fate with that of hydroxypyruvate. The metabolism of hydroxypyruvic acid was compared with that of C1402 fixation in order to ascertain whether it might be a photosynthetic int...
متن کاملSynthesis of D-Glucose-1-C14 and D-Mannose-1-C14
Heretofore, radiochemical yields of sugars position-labeled with carbon-14 have been only 5 to 10 percent. This paper reports an improved cyanohydrin synthesis, and the preparation of D-glucose-1-C and D-mannose-1-C from D-arabinose in yields of about 50 percent. Low yields in prior syntheses appear to have been due to several inefficient steps, and to the fact that extension of the carbon chai...
متن کاملThe metabolism of glycine-2-C14 in man. III. The urinary excretion of C14 and cumulative radiation dosimetry.
Five patients were given 100 microcuries of glycine-2CH4 (8.0 mg.) intravenously; these do not include the four patients whose pulmonary C14 excreted has been reported (1). The time and volume of each spontaneous urinary voiding was noted for the first 10 days; thereafter an aliquot of a spontaneous morning voiding was collected once per week. An aliquot (5 or 10 ml.) was dried in vacuo, then c...
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ژورنال
عنوان ژورنال: Canadian Journal of Chemistry
سال: 1957
ISSN: 0008-4042,1480-3291
DOI: 10.1139/v57-033